Application of a high-throughput quantitative PCR system for simultaneous monitoring of SARS-CoV-2 variants and other pathogenic viruses in wastewaterArticle Published on 2022-12-202022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] acute respiratory syndrome Alpha variant analyzed application applied assays can be used collected Community coronavirus coronavirus disease COVID-19 delta variant demonstrated detect eight epidemiologically FIVE Health High-throughput qPCR highlighting increase Japan L452R labor-intensive likelihood Mie N501Y nine nucleotide nucleotide substitution pathogenic virus pathogenic viruses Pathogenic viruses, SARS-CoV-2 Patient PCR positive prevalent qPCR quantitative PCR quarantine reported RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variant separated Surveillance target tested time-consuming Treatment virus viruses Volume wastewater Wastewater. Yokkaichi [DOI] 10.1016/j.scitotenv.2022.158659 PMC 바로가기
Effects of Boswellia species on viral infections with particular attention to SARS-CoV-2Article Published on 2022-10-012022-11-15 Journal: Inflammopharmacology [Category] COVID19(2023년), SARS, 치료제, [키워드] activity antiviral activity antiviral drugs Antiviral effect antiviral property Boswellia Boswellia species bronchial asthma caused condition COVID-19 pandemic disease drugs Effect Efficacy exhibited Herbal herbal medicine natural Natural therapies pathogenic virus pharmacological plants provided reduction in reported Research SARS-CoV-2 SARS-CoV-2. therapeutic effect Topic Treatment Vaccine Viral diseases viral infection Viral resistance [DOI] 10.1007/s10787-022-01037-4 PMC 바로가기
Conjugated Polymers-Based Biosensors for Virus Detection: Lessons from COVID-19Article Published on 2022-09-102022-11-15 Journal: Biosensors [Category] 치료기술, [키워드] affected biosensor Conjugated conjugated polymers coronavirus disease country COVID-19 COVID-19 detection Critical Diagnosis DNA/RNA diagnostics drugs electrochemical biosensors Evidence Human issue lesson organic field-effect transistors. pandemic pathogenic virus Polymer public health significantly Spread vaccination virus virus virus detection [DOI] 10.3390/bios12090748 PMC 바로가기
Non-PCR Ultrasensitive Detection of Viral RNA by a Nanoprobe-Coupling Strategy: SARS-CoV-2 as an ExampleArticle Published on 2022-09-012022-11-15 Journal: Advanced Healthcare Materials [Category] COVID19(2023년), SARS, 치료기술, [키워드] amplification approach coronavirus 2 COVID-19 detection Developing diagnostic Diseases exhibit feature linear Magnetic nanoparticles moderate nanoprobe-coupling strategy nucleic acid nucleic acid quick detection. pathogenic pathogenic virus polymerase chain reported reporters respiratory RNA SARS-CoV-2 SARS-CoV-2 N SARS-CoV-2 N gene Sensitivity and specificity specificity Viral RNA widespread Zn2+ doping [DOI] 10.1002/adhm.202200031 PMC 바로가기
Comparative Assessment of Filtration- and Precipitation-Based Methods for the Concentration of SARS-CoV-2 and Other Viruses from WastewaterArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 치료기술, 치료제, [키워드] Adenovirus affected Ammonium Analysis approaches assessment centrifugation Characteristics Community Comparative Concentration COVID-19 COVID-19 pandemic develop Enteric viruses Environmental virology Epidemiology evaluated experiments fecal FIVE Genome glycol human respiratory viruses in viral Influenza information Laboratory Mild murine National Other pathogen detection pathogenic virus physico-chemical property public health public health surveillance quantification rapid expansion SARS-CoV-2 SARS-COV-2 infection selected sewage concentration. subsequent Surveillance tested virus virus virus detection virus particle virus titer viruses Volume wastewater [DOI] 10.1128/spectrum.01102-22 PMC 바로가기
Genetically Engineered MRI-Trackable Extracellular Vesicles as SARS-CoV-2 Mimetics for Mapping ACE2 Binding In VivoArticle Published on 2022-08-232022-11-16 Journal: ACS Nano [Category] SARS, 변종, 유전자 메커니즘, [키워드] ACE2 ACE2 receptor approach binding complex coronavirus event EVs Extracellular extracellular vesicle Genetic genetic engineering hazard in vivo Interaction interactions ligand−receptor binding mapping mechanism MRI Mutagenesis mutant pandemic pathogenic virus platform predicted Protein raised RBD Receptor binding domain Safe SARS-CoV-2 subjects superparamagnetic iron oxide nanoparticles (SPIONs) the RBD tissues variant virus virus mimetics. viruses [DOI] 10.1021/acsnano.2c03119 PMC 바로가기
Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses신종 바이러스에 대해 활성을 나타내는 광범위한 항바이러스제로서 타고난 면역 신호의 인핸서 식별Article Published on 2022-07-212022-09-11 Journal: Cell chemical biology [Category] COVID19(2023년), SARS, 치료제, [키워드] active against acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral antiviral activity boost broad-spectrum antiviral broad-spectrum antivirals Compound coronavirus Defense dependent on Drug screening emerging viruses enhancer Factors Gilteritinib identifying Immunity immunomodulatory molecules immunostimulatory IMPROVE increasingly Infection Innate innate immune innate immune activation Innate immunity innate response interferon interferon regulatory factor interferon regulatory factors. IRF7 IRFs Kinase inhibitor kinase inhibitors library nuclear translocation outbreak Pandemics pathogenic virus pathogenic viruses Pathogens proof proof of concept Regulatory RNA viruses SARS-CoV-2 screened severe acute respiratory syndrome Coronavirus Signaling viral infection virus [DOI] 10.1016/j.chembiol.2022.05.009 PMC 바로가기 [Article Type] Article
Detection of Ancient Viruses and Long-Term Viral Evolution고대 바이러스의 탐지 및 장기간의 바이러스 진화Review Published on 2022-06-182022-09-11 Journal: Viruses [Category] 치료기술, [키워드] analyzed ancient DNA ancient RNA ancient virome ancient virus approach bioinformatics complex COVID-19 outbreak detectable detection events human population NGS Pandemics past pathogenic pathogenic virus pathogenic viruses PCR preserved recent RNA Sequencing specimen TDRP tissues unique Usage viral DNA viral evolution viral evolution. viral genome viral genomes virus [DOI] 10.3390/v14061336 PMC 바로가기 [Article Type] Review
Metadichol®: A Novel Nanolipid Formulation That Inhibits SARS-CoV-2 and a Multitude of Pathological Viruses In VitroResearch Article Published on 2022-01-152022-10-27 Journal: BioMed Research International [Category] COVID-19, [키워드] ACE ACE2 acute respiratory syndrome alcohols approach Bacteria Caco-2 cell Camostat mesylate Chloroquine coronavirus coronavirus Critical demonstrated develop entry of SARS-CoV-2 Formulation host cell host cells human host cells Increasing Infection inhibit inhibitor Interaction mechanism membranes multitude Naturally novel outbreak pandemic pathogenic virus pathological performed plasma membrane proliferation promoted receptor ACE2 reduce Remdesivir SARS-CoV-2 SARS-CoV-2 replication saturated serine protease TMPRSS2 Spread time-consuming TMPRSS2 Vaccines viral infectivity viral S protein virus virus [DOI] 10.1155/2022/1558860 PMC 바로가기 [Article Type] Research Article
Metadichol®: A Novel Nanolipid Formulation That Inhibits SARS-CoV-2 and a Multitude of Pathological Viruses In VitroResearch Article Published on 2022-01-152022-10-27 Journal: BioMed Research International [Category] Coronavirus, COVID-19, SARS, [키워드] ACE ACE2 acute respiratory syndrome alcohols approach Bacteria Caco-2 cell Camostat mesylate Chloroquine coronavirus coronavirus Critical demonstrated develop entry of SARS-CoV-2 Formulation host cell host cells human host cells Increasing Infection inhibit inhibitor Interaction mechanism membranes multitude Naturally novel outbreak pandemic pathogenic virus pathological performed plasma membrane proliferation promoted receptor ACE2 reduce Remdesivir SARS-CoV-2 SARS-CoV-2 replication saturated serine protease TMPRSS2 Spread time-consuming TMPRSS2 Vaccines viral infectivity viral S protein virus virus [DOI] 10.1155/2022/1558860 PMC 바로가기 [Article Type] Research Article